About Script TB-500

What this site is

Script TB-500 is an independent editorial project that publishes summaries of the peer-reviewed research literature on TB-500 and its parent protein, thymosin beta-4. We are not a clinic. We do not employ clinicians and we do not provide medical advice. We do not manufacture, sell, or distribute any product. Our work is editorial commentary on publicly available science.

The organizing idea is an evidence-intensity heatmap. The TB-500 and thymosin beta-4 record is not a flat field — it is a steep gradient. Some findings are structurally established or replicated across animal models and run hot; the human story for the fragment is largely empty and runs cold; and a real share of the hottest findings belong to the full-length protein rather than to the TB-500 heptapeptide. We grade each finding by how hot its evidence actually runs, and we flag when a finding's heat is borrowed from the parent protein, so a reader can see the real shape of the record at a glance.

On the name

The word "script" in this site's name is editorial framing — a position the publisher occupies relative to the medicinal-access conversation around TB-500, not a claim about services we provide. We do not write prescriptions, we are not a pharmacy or a compounding facility, and nothing here is dispensed. The legal-status page exists precisely to describe the regulatory landscape accurately — the FDA 503A category, the compounding framework, and the WADA standing — rather than to route anyone toward obtaining the substance.

We read primary sources: PubMed-indexed studies, the FDA's own compounding pages, and the structural and clinical literature. Where a claim is quantitative, we cite the study behind it. Where the evidence is thin, cold, or borrowed from the parent protein, we say so plainly. That is the whole job.

How to read the grading

Every finding on this site carries two marks. The first is a heat grade — how strong the underlying data run, from a cold "no human data" cell to a hot "animal or structurally confirmed" cell. The second is a confidence mark distinguishing whether the evidence is on the TB-500 fragment itself or borrowed from full-length thymosin beta-4. Together they are meant to keep the reading honest: a hot finding that is also a parent-protein finding is shown as both, never flattened into a single confident claim about the fragment.